The mentor’s primary research focus is to evaluate the effects of genetic and environmental factors on brain function. ApoE is a class of apolipoprotein that exists in humans in three isoforms: E2, E3 and E4. The intern selected for this position will work with the mentor using mice expressing human apoE isoforms to assess the role of apoE in the regulation of anxiety, learning and memory. The E4 isoform indicates a risk factor for age-related cognitive decline, Alzheimer's disease, and the development of cognitive impairments following selected environmental challenges. Treatment strategies to improve brain function in humans suffering from neurological diseases are developed based on what is learned in the mouse model. The intern will gain experience in mouse behavioral testing, data analysis and oral presentations. Applicants must have the ability to focus and pay close attention to detail. Applicants must also be reliable, highly motivated, and team players.
Applicants should be aware that on-site parking may be limited and/or unavailable throughout the summer; interns may be required to rely on public transit or alternative transportation (none of the current lab members drive in to the lab).
Females, minorities, students from low-income households, first-generation college-bound students and students with a primary language other than English are especially encouraged to apply.